Title text: Every computer, at the unreachable memory address 0x-1, stores a secret. I found it, and it is that all humans ar—SEGMENTATION FAULT.
This comic is about a play on the dual meaning of the word "pointer". Cueball is playing a computer game in the comic, but he seems to be stuck. So he asks Black Hat for a few tips ("pointers") to get unstuck again. Black Hat wants to be annoying, so he spits out a couple of (seemingly random) 32-bit hexadecimal addresses, which are "pointers" in a programming language. These pointers are used to access a certain location in the computer's memory in order to fulfill a task. Cueball is then annoyed at Black Hat for not answering his question.
A segmentation fault, as referred to in the title text, is a result by accessing invalid memory addresses. If you define a pointer to an invalid address, then try to access the memory location associated with it, you could end up with this exception. The hexadecimal address 0x-1 is one of those invalid access pointers, because it should contain more accurate numbers for a valid 32-bit hexadecimal address.
The ending letters of the pointers are spelling, reading top to bottom, the word ACE. As Cueball is playing a game Black Hat could be additionally saying he's an ace of that game.
- [Cueball is playing a video game, with Black Hat standing behind him.]
- Cueball: Man, I suck at this game. Can you give me a few pointers?
- Black Hat: 0x3A28213A 0x6339392C, 0x7363682E.
- Cueball: I hate you.
- The "pointers" given are interesting in that all the bytes are printable ASCII characters. In this case (and assuming network byte order), ":(!:", "c99,", and "sch.". It is also interesting that the values that are followed by punctuation each end in that punctuation.