1526: Placebo Blocker - Revision history

R128: /* Explanation */ placebo effect vs perception citation

2025-12-08T15:05:27Z

‎Explanation: placebo effect vs perception citation

Lp0 on fire: removed Category:Science using HotCat

2025-11-27T17:26:59Z

removed Category:Science using HotCat

TheusafBOT: Reverted edit 358064 by 172.71.218.182 to 333346

2024-11-28T03:58:56Z

Reverted edit 358064 by 172.71.218.182 to 333346

172.71.218.182 at 03:58, 28 November 2024

2024-11-28T03:58:40Z

Sarah the Pie(yes, the food): /* Placebos */ changed joke citation needed to actual citation needed

2024-01-22T19:31:49Z

‎Placebos: changed joke citation needed to actual citation needed

172.71.242.190: /* Transcript */

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‎Transcript

172.70.206.151: /* Explanation */ wlink

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‎Explanation: wlink

Natg19: /* Transcript */ bilogy

2022-08-09T02:02:43Z

‎Transcript: bilogy

Natg19: /* Transcript */

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‎Transcript

172.69.79.153: Last editor's tyop

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Last editor's tyop

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 Placebo-blockers do actually already exist. A side-effect of the opiate antagonist {{w|Naloxone}} is that it [http://healthland.time.com/2009/08/26/a-neurological-explanation-for-the-placebo-effect/ blocks the placebo effect].
-It should be noted that placebo does not actually improve the objective condition, only the patient's subjective perception of it (i.e. the patients do not get better more than they randomly would, but the placebo makes them think they do).{{Actual citation needed}}
+It should be noted that placebo does not actually improve the objective condition, only the patient's subjective perception of it (i.e. the patients do not get better more than they randomly would, but the placebo makes them think they do). The placebo effect [https://www.health.harvard.edu/newsletter_article/the-power-of-the-placebo-effect is most significant] in treatments for management of pain, fatigue, and nausea, which are more tied to the brain's perception of the state of the body.
 ===Mechanisms of the placebo effect===

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 [[Category:Comics featuring Cueball]]
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 | number    = 1526
 | date      = May 18, 2015
-| title     = Placebo Downloader
+| title     = Placebo Blocker
-| image     = download.png
+| image     = placebo blocker.png
 | titletext = They work even better if you take them with our experimental placebo booster, which I keep in the same bottle.
 }}

@@ Line 2: / Line 2: @@
 | number    = 1526
 | date      = May 18, 2015
-| title     = Placebo Blocker
+| title     = Placebo Downloader
-| image     = placebo blocker.png
+| image     = download.png
 | titletext = They work even better if you take them with our experimental placebo booster, which I keep in the same bottle.
 }}

@@ Line 35: / Line 35: @@
 Placebo-blockers do actually already exist. A side-effect of the opiate antagonist {{w|Naloxone}} is that it [http://healthland.time.com/2009/08/26/a-neurological-explanation-for-the-placebo-effect/ blocks the placebo effect].
-It should be noted that placebo does not actually improve the objective condition, only the patient's subjective perception of it (i.e. the patients do not get better more than they randomly would, but the placebo makes them think they do).{{Citation needed}}
+It should be noted that placebo does not actually improve the objective condition, only the patient's subjective perception of it (i.e. the patients do not get better more than they randomly would, but the placebo makes them think they do).{{Actual citation needed}}
 ===Mechanisms of the placebo effect===

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 ==Explanation==
-This comic is a joke about the difficulty of testing a drug that is supposed to block the placebo effect.
+This comic is a joke about the difficulty of testing a drug that is supposed to block the {{w|placebo effect}}.
 A placebo experiment is used for testing a drug candidate. It has two groups: one that gets a real drug candidate, and one that gets a fake. The placebo effect describes the observation that the group that gets the fake often show signs of having received a working drug - though commonly weaker than in the group that gets an effective real drug.

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 The comic refers to the recent study by Kathryn T. Hall, Joseph Loscalzo, and Ted J. Kaptchuk. (2015) ''[https://dx.doi.org/10.1016/J.MOLMED.2015.02.009 Genetics and the placebo effect: the placebome.]'' Trends in Mol Medicine. Volume 21, Issue 5, May 2015, Pages 285–294 - however, bear in mind that one has to treat studies very carefully ''[https://sciencebasedmedicine.org/ted-kaptchuk-versus-placebo-effects-again/ Kaptchuk vs Placebo]''
-It is possible to test the placebo blocker using three groups: a test group who receive a placebo and a placebo blocker, a control group who receive a placebo bt no blocker, and a second control group who receive no treatment whatsoever, as a lack of treatment is the variable that an actual placebo is designed to control for. Still it might be hard to determine if the pills are having a negative effect or blocking the placebo effect, so multiple trials with multiple illnesses may have to be carried out.
+It is possible to test the placebo blocker using three groups: a test group who receive a placebo and a placebo blocker, a control group who receive a placebo but no blocker, and a second control group who receive no treatment whatsoever, as a lack of treatment is the variable that an actual placebo is designed to control for. Still it might be hard to determine if the pills are having a negative effect or blocking the placebo effect, so multiple trials with multiple illnesses may have to be carried out.
 ==Transcript==