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As with a [[2287: Pathogen Resistance|number of previous strips]], [[Randall]] has a tendency to anthropomorphize both pathogens and the immune system, [[2425: mRNA Vaccine|envisioning the process of infection and immune response as an epic battle]]. In this case, he treats his immune system as he would a child trying to accomplish something difficult, and worries about its emotional reaction.  
 
As with a [[2287: Pathogen Resistance|number of previous strips]], [[Randall]] has a tendency to anthropomorphize both pathogens and the immune system, [[2425: mRNA Vaccine|envisioning the process of infection and immune response as an epic battle]]. In this case, he treats his immune system as he would a child trying to accomplish something difficult, and worries about its emotional reaction.  
  
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The [[:Category:COVID-19 vaccine|COVID-19 vaccine]]s (like all viral inoculations) work by introducing viral proteins into the body, causing the immune system to react as if the actual virus were present, creating the antibodies to fight it. As a result, if the actual virus is introduced, the immune system will have the capacity to quickly eliminate it.  
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The [[:Category:COVID-19 vaccine|COVID-19 vaccine]](like all viral inoculations) works by introducing viral proteins into the body, causing the immune system to react as if the actual virus were present, creating the antibodies to fight it. As a result, if the actual virus is introduced, the immune system will have the capacity to quickly eliminate it.  
  
 
In this comic, [[Cueball]] has just received the COVID-19 vaccine and anthropomorphizes this process. He worries that his immune system is "freaking out", as the vaccine causes the body to 'think' it's under attack and respond as it would to a deadly threat. Cueball accordingly tries to reassure his immune system that the threat isn't real. However, [[Megan]] reminds him that the "panic" is the entire point, as that's what causes the body to build defenses, which will allow it to handle the real virus. Cueball then switches tactics, melodramatically announcing that the virus is about to kill him, and encouraging his "heroic immune cells" to save the day. The joke is that the basic elements of their response is accurate: the vaccine is essentially a ruse intended to "trick" the immune system into developing antibodies. However, the immune system obviously lacks a separate consciousness, and can neither hear nor understand their comments,{{Citation needed}} making both reassurance and encouragement entirely moot.   
 
In this comic, [[Cueball]] has just received the COVID-19 vaccine and anthropomorphizes this process. He worries that his immune system is "freaking out", as the vaccine causes the body to 'think' it's under attack and respond as it would to a deadly threat. Cueball accordingly tries to reassure his immune system that the threat isn't real. However, [[Megan]] reminds him that the "panic" is the entire point, as that's what causes the body to build defenses, which will allow it to handle the real virus. Cueball then switches tactics, melodramatically announcing that the virus is about to kill him, and encouraging his "heroic immune cells" to save the day. The joke is that the basic elements of their response is accurate: the vaccine is essentially a ruse intended to "trick" the immune system into developing antibodies. However, the immune system obviously lacks a separate consciousness, and can neither hear nor understand their comments,{{Citation needed}} making both reassurance and encouragement entirely moot.   

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